Positively Charged Dual Layered PES Capsule Filter (Pharmaceutical Grade) – DPPC

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The DPPC Filter is constructed with a dual-layer, positively charged PES membrane and is engineered for sterilizing-grade filtration and endotoxin reduction in critical applications. Designed with a bioburden reduction prefilter layer and a sterilizing-grade final membrane, DPPC filters provide absolute bacteria retention while removing negatively charged contaminants such as endotoxins, viruses, and cell fragments. This configuration allows for flexible pore size combinations to match system requirements while maintaining consistent performance from lab scale to full production.

Key Features:

• Dual-Layer PES Membrane: Bioburden reduction prefilter with sterilizing-grade final layer
• Positively Charged Media: Enhances removal of endotoxins and biological contaminants
• Sterilizing-Grade Filtration: Validated for absolute bacteria retention
• Configurable Pore Structure: Multiple prefilter and final layer options available
• High Throughput: Designed for efficient processing in critical applications
• Integrity Tested: Validated and flushed to reduce extractables

Performance Parameters:

• Max Operating Temp (Water): 180 °F at 30 psid (cartridge), 110 °F at 30 psid (capsule)
• Forward Pressure Limit: 80 psid at 68 °F
• Reverse Pressure Limit: 50 psid at 68 °F
• Recommended Changeout: 35 psid
• Max Operating Pressure (Capsule): 80 psi liquid / 60 psi gas at 68 °F

Sterilization & Cleaning:

• Autoclave: 250 °F (121 °C), 30 min, 25+ cycles
• Inline Steam: 275 °F (135 °C), 30 min, 25+ cycles (cartridge)
• Hot Water: 194 °F (90 °C), 30 min, max 3 psid forward
• Compatible with hydrogen peroxide, peracetic acid, sodium hypochlorite, and other standard sanitants

Filtration Area (Nominal):

• 2" – 1.0 ft² (0.10 m²)
• 5" – 2.9 ft² (0.27 m²)
• 10" – 6.1 ft² (0.57 m²)
• 20" – 12.2 ft² (1.14 m²)
• 30" – 18.3 ft² (1.71 m²)
• 40" – 24.4 ft² (2.28 m²)

Construction Materials:

• Filtration Media: Dual-layer positively charged PES membrane (absolute rated)
• Support Cage & Core: Polypropylene
• Sealing Method: Thermal bonding
• O-Rings (Cartridges only): Buna, Viton® (FKM), EPDM, Silicone, FEP-encapsulated options

Validated Microbial Retention:

• 0.03 µm: Acholeplasma laidlawii
• 0.10 µm: Brevundimonas diminuta
• 0.10M µm: Acholeplasma laidlawii
• 0.22 µm: Brevundimonas diminuta (sterilizing grade)
• 0.45 µm: Serratia marcescens

Typical Applications:

• Process water
• Water for Injection (WFI)
• Biopharmaceutical fluids
• Sterile filtration processes
• Endotoxin-sensitive applications