20 Inch Single Layer Pharmaceutical Grade Filter Capsule (SPSXPGC)

Click here for more information

The SPSX Capsule Filter features a single-layer, asymmetric Polyethersulfone (PES) membrane designed for validated sterilizing-grade filtration of aqueous liquids. With pore sizes ranging from 0.03 to 1.2 µm, SPSX filters offer high flow, broad chemical compatibility, and consistent performance from lab to production scale. Their low protein and preservative binding characteristics make them ideal for sensitive formulations in pharmaceutical and bioprocessing applications.

Key Features:

• Validated 0.03–1.2 µm absolute-rated PES membrane
• Low extractables and low protein binding
• High flow rates with wide pH compatibility
• 100% integrity tested and USP-compliant
• Available pre-sterilized

Performance Parameters:

• Max Operating Temp: 110 °F at 30 psid (43 °C at 2.07 bard)
• Forward Differential Pressure: 80 psid at 68 °F (5.52 bard)
• Reverse Differential Pressure: 50 psid at 68 °F (3.45 bard)
• Recommended Changeout Pressure: 35 psid (2.41 bard)

Sterilization & Cleaning:

• Filtered Hot Water: 90 °C (194 °F), 30 min, multiple cycles, max 3 psid
• Autoclave: 250 °F (121 °F), 30 min, 25+ cycles
• Inline Steam (Cartridge Only): 275 °F (135 °C), 30 min, 25+ cycles
• Chemical Sanitization: Compatible with hydrogen peroxide, peracetic acid, sodium hypochlorite, and other standard chemicals

Filtration Area (Nominal):

• 2" – 1.2 ft² (0.11 m²)
• 5" – 3.4 ft² (0.32 m²)
• 10" – 7.3 ft² (0.68 m²)
• 20" – 14.6 ft² (1.36 m²)
• 30" – 21.9 ft² (2.04 m²)
• 40" – 29.2 ft² (2.72 m²)

Diffusion & Bubble Point (Water-Wetted):

Diffusion Specifications (All Pore Sizes):

• 2" – ≤ 2.9 mL/min
• 5" – ≤ 8.6 mL/min
• 10" – ≤ 20 mL/min
• 20" – ≤ 40 mL/min
• 30" – ≤ 60 mL/min
• 40" – ≤ 80 mL/min

Typical Applications:

• SVPs & LVPs
• Water for Injection (WFI)
• Vaccines
• Diagnostics
• Buffers
• Ophthalmics
• Biologicals

Construction Materials:

• Filtration Media: Single Layer Asymmetric PES Membrane
• Support Layers, Cage, Core, Housing: Polypropylene
• Sealing: Thermal Bonding
• Gasket/O-Ring Options (Cartridge Only): Buna, Viton® (FKM), EPDM, Silicone, FEP-Encapsulated Silicone or Viton®

Regulatory & Quality Compliance:

• Validated per ASTM F 838-15(ae1) with >7-log retention of:
 - Acholeplasma laidlawii (0.03 µm)
 - Brevundimonas diminuta (0.10 & 0.22 µm)
 - Serratia marcescens (0.45 µm)
 - Saccharomyces cerevisiae (0.65 µm)
• USP <643> TOC and <645> Conductivity Compliant
• USP Class VI Biological Reactivity Compliant
• Non-Fiber Releasing (21 CFR 210.3(b)(6), 211.72)
• FDA Compliant for Food Contact (21 CFR 174.5, 177.1500, etc.)

Let me know if you’d like help uploading this to Shopify or preparing more descriptions.