High Capacity Dual Layered Polyethersulfone Membrane Filter Capsule (HPPSXPGC)

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The HPPSX Capsule Filter features a dual-layer Polyethersulfone (PES) membrane designed to handle sterile filtration of high-particulate aqueous fluids. With a high-capacity PES prefilter layer and an asymmetric PES final filter layer, HPPSX ensures high flow rates, broad chemical compatibility, and excellent retention performance across a wide pH range.

Its low protein-binding properties make HPPSX ideal for critical biopharmaceutical and diagnostic applications. Each unit is flushed to reduce extractables and is 100% integrity tested. Pre-sterilized capsule formats are also available.

Key Features:

• Dual-Layer PES Membrane: High-capacity prefilter + asymmetric final layer
• Sterilizing-Grade Performance: Validated >7-log microbial retention
• Low Binding: Ideal for proteins, preservatives, and sensitive formulations
• FDA & USP Class VI Compliant: Non-toxic and safe for medical applications
• Pre-Sterilized Option: Available for ready-to-use convenience

Performance Parameters:

• Max Operating Temp (Water): 110 °F at 30 psid (43 °C at 2.07 bar)
• Forward Pressure Limit: 80 psid at 68 °F
• Reverse Pressure Limit: 50 psid at 68 °F
• Recommended Changeout: 35 psid

Sterilization & Cleaning:

• Autoclave: 250 °F (121 °C), 30 min, 25+ cycles
• Inline Steam: 275 °F (135 °C), 30 min
• Hot Water: 194 °F (90 °C), 30 min, max 3 psid forward
• Compatible with H₂O₂, peracetic acid, bleach, etc.

Filtration Area (Nominal):

• 2" – 0.9 ft² (0.08 m²)
• 5" – 2.5 ft² (0.23 m²)
• 10" – 5.4 ft² (0.50 m²)
• 20" – 10.8 ft² (1.00 m²)
• 30" – 16.2 ft² (1.51 m²)
• 40" – 21.6 ft² (2.01 m²)

Construction Materials:

• Filtration Media: Dual-layered PES (high capacity + asymmetric)
• Support Cage & Housing: Polypropylene
• Sealing Method: Thermal bonding
• O-Rings: Buna, Viton® (FKM), EPDM, Silicone, FEP-encapsulated options

Typical Applications:

• SVPs & LVPs
• Diagnostics
• Buffers
• Vaccines
• WFI & water purification
• Biologicals
• Ophthalmic solutions